B Positive Theme Song
Comedy Theme Song Archive

B Positive Theme Song And Lyrics

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Song TitleB Positive (Theme Song)
ArtistsKeb’ Mo’ (S1) / Annaleigh Ashford (S2)
Created ByMarco Pennette
Total Episodes34
NetworkCBS
Premiere DateNovember 5, 2020
GenreSitcom

B Positive Theme Song Lyrics

The more you give the more you give The more you live the more you live And your happiness happiness Is relative but if you’re But if you’re feeling like crap It’s time to face the fact It’s your prerogative your prerogative To be positive

Behind the Tune: Meaning & Story

The theme song for B Positive is a rare example of a sitcom intro that evolved significantly during its broadcast run. Originally composed with a bluesy, soulful feel by legendary musician Keb’ Mo’, the song underwent a stylistic shift in the second season. From the third episode of Season 2 onward, the vocals were taken over by series lead Annaleigh Ashford, reflecting the show’s transition from a narrow focus on kidney donation to a broader ensemble comedy set in an assisted living facility.

The lyrics emphasize the “circular” nature of altruism—the idea that giving to others directly enriches one’s own life. The title itself is a clever triple entendre: it refers to the blood type needed for the transplant (B-Positive), the protagonist’s name (Drew), and the optimistic mindset required to face life-threatening health challenges.

Created by Marco Pennette, the show used this upbeat track to balance the heavy subject matter of organ failure with the lighthearted, resilient spirit of its characters, Drew and Gina.

Frequently Asked Questions

What is the main plot of the series?
B Positive tells the story of Drew, a recently divorced therapist in search of a kidney donor, and Gina, a rough-around-the-edges acquaintance from his past who happens to be a match and offers him a second chance at life.
Why did the theme song singer change?
The change occurred in Season 2 to align with a soft reboot of the show’s premise. Having Annaleigh Ashford (Gina) sing the theme reflected her character’s more central role as she began managing a retirement home.
Was B Positive renewed for Season 3?
No, CBS officially canceled the series in May 2022, following the conclusion of its second season. The show finished with a total of 34 episodes.
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Editorial Note: Theme history and artist credits for B Positive have been curated by the ThemeSong.info Editorial Team to reflect the musical transitions between Season 1 and Season 2.